Vaporized Hydrogen Peroxide (VH₂O₂) is now recognized as a reference technology for airborne surface decontamination in high-criticality environments: sterile areas, GMP laboratories, hospitals, and pharmaceutical or biotech production sites.

At Solidfog, we have chosen to dedicate a large part of our activities to the research, development, and optimization of VH₂O₂ systems. Our objective: to deliver efficient, safe solutions that fully comply with international regulatory requirements.

Our technology is based on a fine and controlled nebulization of H₂O₂, ensuring homogeneous distribution of the biocide across treated volumes, regardless of geometric or airflow constraints.

VH₂O₂ technology dedicated to critical environment biodecontamination

Our VH₂O₂ surface disinfection systems are the result of over 20 years of field experience and continuous innovation. Through careful atomizer design, precise biocide pump control, and rigorous pressure regulation, we ensure reproducible and effective decontamination in line with the highest validation standards.

Key benefits of our technology include:

  • Homogeneous diffusion of hydrogen peroxide throughout the volume
  • Reliable and reproducible biodecontamination cycles
  • Compatibility with sensitive materials, with no corrosion or residues
  • Full control of critical parameters (pressure, concentration, humidity, flow rate)
  • Compliance with GMP procedures
  • Validatable results according to EN 17272 – LOG6 performance
  • Automated data recording for audit-ready documentation

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Our VH₂O₂ decontamination integration and qualification methodology

With our extensive field experience and expertise in airborne decontamination, we provide tailored technical support at every stage of your project. Depending on the specific constraints of your environment (airflow characteristics, volumes, pressure, humidity, etc.), our engineers recommend optimal parameters to ensure process efficiency and reproducibility.

This includes:

  • The number and positioning of injection points
  • Their orientation within the space
  • Atomization flow rate
  • Biocide quantity and concentration
  • Exposure time required to achieve the targeted decontamination level (e.g., LOG6)

This rigorous methodology allows us to meet validation requirements while ensuring safety, compliance, and cycle performance.

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Scientific basis of VH₂O₂: effectiveness, parameters, and validation

VH₂O₂ is generated from aqueous hydrogen-peroxide solutions, typically between 6 % and 35 % concentration, atomised into microdroplets that provide direct sporicidal contact on surfaces and in the air.
Process efficiency depends on several interrelated factors such as droplet size, relative humidity, contact time, and uniformity of diffusion. When these parameters are properly balanced, controlled micro-condensation occurs: a fine, invisible film of concentrated H₂O₂ that enhances contact with microorganisms and significantly increases sporicidal efficacy.

Solidfog systems integrate and monitor these parameters within a controlled protocol validated with biological, enzymatic, and chemical indicators, in full alignment with EN 17272 and GMP qualification requirements.

Process effectiveness depends not only on concentration, but also on other parameters such as:

  • Droplet size
  • Relative humidity rate
  • Contact time
  • Uniformity of diffusion within the space

Our systems integrate these variables into a controlled protocol, validated with biological and chemical indicators, in full compliance with qualification and validation requirements.

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Solidfog: your technology partner for reliable and validatable VH₂O₂ biodecontamination

We do not simply provide a technology, but a complete and fully controlled VH₂O₂ decontamination solution, tailored to the most demanding environments.

Our approach combines scientific rigor, technical innovation, and personalized support to ensure performance, traceability, and compliance for every biodecontamination cycle.

Whether your sector is pharmaceutical, hospital, biotechnology, or research, we work with you to design, qualify, and optimize a customized system validated according to applicable standards.

Would you like to learn how our decontamination solutions can meet your operational needs ?

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